Sulfur: “Mineral of Beauty”

         Sulfur (= Sulfur) (S)

         For humans – “the mineral of beauty”.
          
     In the bodies of animals and humans sulfur performs essential functions: it ensures the spatial organization of protein molecules necessary for their functioning, protects cells, tissues, and biochemical synthesis pathways from oxidation, and the entire organism from the toxic effects of foreign substances.

 
    The daily requirement for sulfur in the human body is 0.5–3 g (according to other data – 4–5 g).
 

    Sulfur enters the body through food products, in the form of inorganic and organic compounds. Most of the sulfur enters the body as part of amino acids.
    Inorganic sulfur compounds (sulfates and sulfites) are not absorbed and are excreted from the body with feces. Organic protein compounds are broken down and absorbed in the intestine.

 

    The sulfur content in the body of an adult human is about 0.16% (110 g per 70 kg body weight). Sulfur is present in all tissues of the human body, particularly abundant in muscles, skeleton, liver, nervous tissue, and blood. The outer layers of the skin are also rich in sulfur, where it is part of keratin and melanin.
    In tissues, sulfur exists in a variety of forms – both inorganic (sulfates, sulfites, sulfides, thiocyanates, etc.) and organic (thiols, thioethers, sulfonic acids, thiourea, etc.). In the form of sulfate anion, sulfur is present in the liquid media of the body. Sulfur atoms are integral components of the molecules of essential amino acids (cystine, cysteine, methionine), hormones (insulin, calcitonin), vitamins (biotin, thiamine), glutathione, taurine, and other important compounds for the body. In their composition, sulfur participates in redox reactions, tissue respiration processes, energy production, genetic information transfer, and performs many other important functions.
    Sulfur is a component of the structural protein collagen. Chondroitin sulfate is found in skin, cartilage, nails, ligaments, and heart valves. Important sulfur-containing metabolites also include hemoglobin, heparin, cytochromes, fibrinogen, and sulfolipids.

 

    Sulfur is primarily excreted in urine as neutral sulfur and inorganic sulfates, with a smaller portion being eliminated through the skin and lungs, and mainly excreted in urine as SO42–.
    Endogenous sulfuric acid, formed in the body, participates in detoxifying toxic compounds (phenol, indole, etc.) produced by intestinal microflora, and also binds foreign substances, including drugs and their metabolites. As a result, harmless compounds – conjugates – are formed, which are then excreted from the body.
    Sulfur metabolism is regulated by those factors that also have a regulatory effect on protein metabolism (hormones of the pituitary gland, thyroid, adrenal glands, and gonads).

 

    Biological role in the human body. In the human body, sulfur is an essential component of cells, enzymes, hormones, particularly insulin, which is produced by the pancreas, and sulfur-containing amino acids (methionine, cysteine, taurine, and glutathione).
    Sulfur is part of biologically active substances (histamine, biotin, lipoic acid, etc.). The active centers of the molecules of a number of enzymes contain SH groups, which participate in many enzymatic reactions, particularly in creating and stabilizing the native three-dimensional structure of proteins, and in some cases act directly as catalytic centers of enzymes; they are part of various coenzymes, including coenzyme A.
    Sulfur is a component of hemoglobin, is present in all tissues of the body, and is necessary for collagen synthesis – a protein that determines the structure of the skin.
    In the cell, sulfur ensures such a delicate and complex process as energy transfer: it carries electrons by accepting one of the unpaired electrons of oxygen onto a free orbital. Sulfur participates in the fixation and transport of methyl groups.

 

     Sulfur disinfects the blood, increases the body’s resistance to bacteria, and protects the protoplasm of cells, facilitates necessary oxidative reactions in the body, enhances bile secretion, protects against the harmful effects of toxic substances, shields the body from harmful effects of radiation and environmental pollution, thereby slowing down the aging processes. This explains the high demand of the body for this element.

 

    Synergists and antagonists of sulfur. Elements that promote sulfur absorption include fluorine and iron, while antagonists include arsenic, barium, lead, molybdenum, and selenium.

 

    Signs of sulfur deficiency: constipation, allergies, dullness and hair loss, brittle nails, high blood pressure, joint pain, tachycardia, high blood sugar, and high triglyceride levels in the blood.
    In severe cases – fatty liver dystrophy, kidney hemorrhages, disturbances in protein and carbohydrate metabolism, overstimulation of the nervous system, irritability.
    Sulfur deficiency in the body is not common, as most food products contain sufficient amounts of it.

 

    In recent decades, one of the sources of excessive sulfur intake in the human body has been sulfur-containing compounds (sulfites) that are added to many food products, alcoholic and non-alcoholic beverages as preservatives. Particularly high levels of sulfites are found in smoked foods, potatoes, fresh vegetables, beer, cider, ready-made salads, vinegar, and wine colorants. It is possible that the constantly increasing consumption of sulfites is partially responsible for the rise in the incidence of bronchial asthma. It is known, for example, that 10% of patients with bronchial asthma exhibit increased sensitivity to sulfites (i.e., they are sensitized to them). To reduce the negative impact of sulfites on the body, it is recommended to increase the intake of cheeses, eggs, fatty meats, and poultry.

 

    Major manifestations of sulfur excess in the body: itching, rash, furunculosis, redness and swelling of the conjunctiva; appearance of small pinpoint defects on the cornea; aching in the eyebrows and eyeballs, sensation of sand in the eyes; photophobia, tearing, general weakness, headaches, dizziness, nausea, upper respiratory tract catarrh, bronchitis; hearing impairment, digestive disorders, diarrhea, weight loss; anemia, mental disorders, decreased intelligence.

 

    Sulfur is necessary: in pulmonary tuberculosis, joint rheumatism, inflammations, heartburn, arthritis, rhinitis, hair problems (when the amount of keratin in them is below normal), joint pain, parasitic infections, irritable bowel syndrome, carpal tunnel syndrome (a professional disease of computer workers), as well as skin and nail diseases.

 

    Food sources of sulfur: vegetables: garlic, onion, cabbage, broccoli, Brussels sprouts, cauliflower, kelp, hot pepper, black radish, celery, asparagus, horseradish, white and black mustard; greens: arugula, celery greens, garlic greens; nuts and seeds: poppy, macadamia, almond, Brazil nut, walnut, pine nut, sunflower seeds, pumpkin seeds, pistachios, hazelnut; legumes: beans, peas, soybeans, kidney beans, lentils; grains: corn, oats, soft wheat, hard wheat; wheat germ; eggs (yolks), fish, meat.
    Sulfur is the main mineral that makes garlic the “king of plants”.

 

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